CACMLE Hematology Courses

105-Online: Thalassemia – The Molecular Biology

$48.00

Contact Hours (Points): 4

This updated self-study course is designed to provide a review of the clinical and diagnostic features of alpha and beta thalassemia and discuss the molecular aspects of these diseases. Traditional and modern molecular systems will be presented and applied to the diagnosis of various forms of thalassemia. The exam to this course remains unchanged since 2007, except for one question change in 2012.

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Product Description

Thalassemia: The Molecular Biology

Self-Study 105 – Intermediate Level

Contact Hours (Points): 4

Written by Tim R. Randolph MS, MT(ASCP)

Published 2003. Updated 2012.

Online – 105: Course Taken Online: $48.00 BUY NOW

IMPORTANT: This online course is accessible using the following:

Desktop or Laptop Computer – Download the latest Adobe Reader program.

Kindle Fire – No additional App download is necessary.

Apple iPad (all versions) / Nook / Kindle – Recommend purchase of a PDF Reader App, such as GoodReader, Cloudreaders, or Stanza by Amazon. Once downloaded, launch this App to access the course online site in order to logon to and view your course.

Here’s what satisfied customers have to say~

“This course was above the level I was hoping for.
But I feel that I am now much more knowledgeable about Thalassemia.”
~Linda F.

“It was more difficult than expected, but I learned quite a bit more than I anticipated.“
~Roxanne D.

“Very detailed and great images to show concepts.“
~Hayley S.

“Great upgrade for my knowledge base.“
~Michael S.

TABLE OF CONTENTS

SECTION I: NORMAL STRUCTURE AND EXPRESSION OF GLOBIN GENES

Normal Globin Gene Structure, Normal Hemoglobin Synthesis and Structure, Normal Gene Processing

SECTION II: COMMON MOLECULAR DEFECTS IN THALASSEMIA

Gene Deletion, Promoter Mutation, Mutated Stop Codon, Nonsense Mutation, Splice Site Mutation

SECTION III: GLOBIN GENE EXPRESSION AND SYMPTOMATOLOGY

Two Levels of Gene Expression, Genotype verses Phenotype Classification of Thalassemias, Four Genotypes of -Thalassemia, Four Phenotypes of -Thalassemia

SECTION IV: TRADITIONAL AND FUTURE MOLECULAR DIAGNOSTIC APPROACHES

Restriction Fragment Length Polymorphism (RFLP), Southern Blot, Dot Blot, High Pressure Liquid Chromatography (HPLC), Polymerase Chain Reaction (PCR), Microarray Technology, mDx AlphaGene 1, mDx AlphaGene 2, mDx AlphaGene 3, mDx BeTha Gene 1

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