Thalassemia: The Molecular Biology
Self-Study 105 – Intermediate Level
Contact Hours (Points): 4
Written by Tim R. Randolph MS, MT(ASCP)
Published 2003. Updated 2012.
Online – 105: Course Taken Online: $48.00 BUY NOW
IMPORTANT: This online course is accessible using the following:
Desktop or Laptop Computer – Download the latest Adobe Reader program.
Kindle Fire – No additional App download is necessary.
Apple iPad (all versions) / Nook / Kindle – Recommend purchase of a PDF Reader App, such as GoodReader, Cloudreaders, or Stanza by Amazon. Once downloaded, launch this App to access the course online site in order to logon to and view your course.
Here’s what satisfied customers have to say~
“This course was above the level I was hoping for.
But I feel that I am now much more knowledgeable about Thalassemia.”
“It was more difficult than expected, but I learned quite a bit more than I anticipated.“
“Very detailed and great images to show concepts.“
“Great upgrade for my knowledge base.“
TABLE OF CONTENTS
SECTION I: NORMAL STRUCTURE AND EXPRESSION OF GLOBIN GENES
Normal Globin Gene Structure, Normal Hemoglobin Synthesis and Structure, Normal Gene Processing
SECTION II: COMMON MOLECULAR DEFECTS IN THALASSEMIA
Gene Deletion, Promoter Mutation, Mutated Stop Codon, Nonsense Mutation, Splice Site Mutation
SECTION III: GLOBIN GENE EXPRESSION AND SYMPTOMATOLOGY
Two Levels of Gene Expression, Genotype verses Phenotype Classification of Thalassemias, Four Genotypes of -Thalassemia, Four Phenotypes of -Thalassemia
SECTION IV: TRADITIONAL AND FUTURE MOLECULAR DIAGNOSTIC APPROACHES
Restriction Fragment Length Polymorphism (RFLP), Southern Blot, Dot Blot, High Pressure Liquid Chromatography (HPLC), Polymerase Chain Reaction (PCR), Microarray Technology, mDx AlphaGene 1, mDx AlphaGene 2, mDx AlphaGene 3, mDx BeTha Gene 1