Autoimmune Diseases: Etiology, Symptomatology, and Laboratory Diagnosis
Self-Study 136 – Intermediate Level
Contact Hours (Points): 12
Written by Maribeth Flaws, PhD, SM(ASCP)SI and Diane Cearlock, PhD, MT(ASCP)
Published 2007. Updated 2010.
Online – 136: Course Taken Online: $120.00 BUY NOW
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TABLE OF CONTENTS
SECTION I: INTRODUCTION
SECTION II: DEFINITION OF AUTOIMMUNITY
SECTION III: IMMUNE TOLERANCE
Central Tolerance; T lymphocyte Tolerance; Peripheral Tolerance; Activation-induced cell death; Absence of co-stimulation; Ignorance (failure to recognize self antigen); Regulation of immune responses by Thelper cells; Breakdown of Tolerance and Development of Autoimmunity; Genetic predisposition to autoimmune disease; Environmental triggers to autoimmune disease development; Hormonal influences on autoimmune disease; Breakdown of self- tolerance
SECTION IV: MECHANISMS OF AUTOIMMUNE DISEASE
SECTION V: LABORATORY DIAGNOSIS OF AUTOIMMUNE DISEASES
Acute Phase Reactants; Serum Protein Electrophoresis; Complement; Evaluation; Autoantibodies; Antinuclear Antibodies; Anti-Cytoplasmic Antibodies; Anti-Neutrophil Cytoplasmic Antibodies (ANCA); Anti-Tissue Antibodies; Rheumatoid Factor
SECTION VI: ORGAN SPECIFIC AUTOIMMUNE DISEASES
Autoimmune Diseases of the Thyroid; Graves Disease; Hashimotos Thyroiditis; Autoimmune Diseases of the Stomach And Intestines; Pernicious anemia; Crohns Disease; Ulcerative colitis; Autoimmune Diseases of the Liver; Autoimmune Hepatitis; Primary Biliary Cirrhosis; Autoimmune Diseases of the Nervous System; Myasthenia Gravis; Multiple Sclerosis (MS); Autoimmune Disease of the Pancreas: Type I Diabetes Mellitus; Autoimmune Disease of the Adrenal Gland: Addisons Disease
SECTION VII: ORGAN NON-SPECIFIC AUTOIMMUNE DISEASES
Systemic Lupus Erythematosus; Drug-Induced Lupus; Rheumatoid Arthritis (RA); Progressive Systemic Sclerosis (Scleroderma); Mixed Connective Tissue Disease; Sjogrens Syndrome (SS); Polymyositis and Dermatomyositis; Systemic Vasculitides