CACMLE Chemistry & Urinalysis Courses

146-Online: Understanding the Renal System and Testing for Disease


Contact Hours (Points): 6

The renal system is a complex, intricate system that regulates and impacts many of the processes that occur within the body. In order to understand what happens in renal disease, one must understand what is considered normal. This course examines renal system anatomy and physiology outlining the structure and function of the system. It then follows with the laboratory’s role in diagnosing renal disease by presenting laboratory testing and disease presentation.

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Product Description

Understanding the Renal System and Testing for Disease

Self-Study 146 – Basic to Intermediate Level

Contact Hours (Points): 6

Written by Amy Thompson PhD, MT(ASCP)

Published 2009. Reviewed 2013. Reformatted 2015.

Upon completion of this course, the learner will be able to:
~ Understand urinary system/renal system anatomy and physiology. Urinary system/renal system anatomy and physiology will be discussed so that the participant might recognize what is normal anatomy and physiology and what is changed in pathophysiological conditions.
~ Explain the pathophysiology of renal disease by understanding normal anatomy and physiology. The participant will learn about changes that occur in pathophysiological conditions involving the kidney and affecting the body as a whole.
~ Interpret laboratory values associated with normal and disease states.

Laboratory values will be described in regards to what is considered normal and what abnormal changes occur with certain disease states.

Online – 146: Course Taken Online: $72.00 BUY NOW
IMPORTANT: This online course is accessible using the following:

Desktop or Laptop Computer –

  • Download the latest free Adobe Reader program.
  • Download the latest free Adobe Flash Player program.
  • Use Windows Explorer as your browser when accessing this course on the “courses online” site.

Due to the dual-format nature of this course, do NOT use tablets to access this course. This includes: Kindle Fire, Apple iPad (all versions), Nook, and Kindle.



Urinary sytem overview; Differences between male and female urinary systems; Urinary bladder; Kidney Anatomy; Exterior Kidney; Interior Kidney; Renal vasculature; Nephron; Renal Corpuscle; Glomerular capillaries; Basement membrane and surrounding cells; Juxtaglomerular apparatus; Proximal and distal convoluted tubules, the loop of Henle, and collecting duct


Formation of urine; Filtration; Filtration based on size; Filtration based on pressure; Review of Concepts; Reabsorption; Proximal convoluted tubule; Loop of Henle; Distal convoluted tubule; Renin-Angiotensin-Aldosterone System; Secretion; Regulatory and endocrine function; Acid-Base balance at the level of the kidneys; Water and electrolyte homeostasis; Water and sodium; Potassium; Other electrolytes; Endocrine function; Erythropoietin; Vitamin D; Prostaglandins


Non-protein nitrogenous wastes; Urea; Production of urea; Changes in urea concentration; Urea methodology; Creatinine; Production of creatinine; Changes in creatinine concentration; Creatinine methodology; Urea:creatinine ratio; Uric acid; Production of uric acid; Changes in uric acid concentration; Uric acid methodology; Ammonia; Production of ammonia; Changes in ammonia concentration; Ammonia methodology; Glomerular filtration rate; Creatinine clearance; Creatinine clearance formulas; Factors that affect glomerular filtration rate; Urinary proteins; Microalbumin; Bence-Jones Protein; Uromodulin (Tamm-Horsfall Protein); Myoglobin; Concentrating ability; Osmolality; Specific gravity; Challenge: Diabetes mellitus or diabetes insipidis; Electrolytes


Glomerular disease; Acute glomerulonephritis; Chronic glomerulonephritis; Nephrotic syndrome; Loss of renal function; Acute renal failure; Chronic kidney disease; Urinary tract infection; Nephropathy; Renal obstruction; Tubular disorders; Fanconi’s Syndrome; Renal tubular acidosis


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