The Gift that Keeps on Giving: Herpes Simplex and Varicella Zoster Virus
Self-Study 207 – Basic to Intermediate Level
Contact Hours (Points): 3
Written by Perry M. Scanlan, PhD, MT(ASCP)
Published 2011. Reviewed 2014.
This step-by-step guide to herpes and varicella zoster infections illustrates how infection relates to disease, diagnosis, and treatment. At the conclusion of this course, the learner will be able to:
- 1. Name all eight human herpes viruses.
- 2. Describe the general and genomic structure of alphaherpesviruses.
- 3. Label the parts of Herpes Simplex Virus.
- 4. Appreciate the capsid structure and its symmetry.
- 5. Identify the viral glycoproteins in the viral envelope.
- 6. List and discuss the steps in viral entry.
- 7. Appreciate the complexity of the viral entry mechanism.
- 8. List and discuss the function of glycoproteins and their receptors.
- 9. Correlate the herpetic lesion to multinucleate giant cell formation.
- 10. Identify the location of viral DNA in infected cells.
- 11. Explain the Central Dogma of Genetics.
- 12. Define important terms of viral control.
- 13. Describe and discuss the control of immediate early, early, and late genes.
- 14. Describe the difference between genes and their functional products in viral control.
- 15. Identify the location of DNA replication, encapsidation, and egress.
- 16. List and describe viral entry through egress.
- 17. Define HSV and VZV latency.
- 18. Estimate the number of people with HSV disease.
- 19. Associate HSV-1 and HSV-2 with body location and most common manifestations.
- 20. Extrapolate the relative risk of HSV-1 and HSV-2 to demographic populations.
- 21. List and describe the diseases of HSV-1 and HSV-2
- 22. Appreciate the social stigma associated with HSV-1 vs. HSV-2.
- 23. Compare and contrast the different ways HSV-1 and HSV-2 are spread.
- 24. List and discuss the steps in VZV entry.
- 25. Appreciate the complexity of the VZV entry mechanism.
- 26. List and discuss the function of glycoproteins and their receptors.
- 27. Describe the genome structure of VZV.
- 28. List and describe the diseases of VZV
- 29. Compare and contrast the different ways Chicken pox and shingles are manifested.
- 30. Describe which age populations are most at risk for VZV diseases.
- 31. List and distinguish the complications associated with VZV infection.
- 32. Describe the model of primary VZV infection and spread.
- 33. Predict the area of vesicular rash during reactivation of VZV from specific DRG.
- 34. Describe the proper specimen collection and transport for isolating HSV and VZV.
- 35. List and describe the main methods of diagnostic testing for alphaherpesviruses.
- 36. Differentiate between the cell lines used in cell culture.
- 37. Evaluate the combination of cells needed to identify alphaherpesvirus in cell culture.
- 38. Compare and contrast the advantage and disadvantages of each diagnostic testing method.
- 39. List and describe the over-the-counter treatments for HSV and VZV.
- 40. List and describe the prescription treatments for HSV and VZV.
- 41. Discuss how guanine nucleoside analogs inhibit HSV and VZV.
- 42. List and describe treatments for drug resistant HSV and VZV.
- 43. Recommend VZV vaccines for the prevention of chicken pox and shingles.
The course serves as an excellent resource to educate students or working professionals who are interested in acquiring knowledge in this particular area of virology.
Presented in an easy-to-use PowerPoint slide format with corresponding audio, it’s just like being at a live presentation!
Online 207: Course Taken Online: $40.00 BUY NOW
IMPORTANT: This online course is NOT downloadable; and is accessible using the following:
Desktop or Laptop Computer – Download the Adobe Flash program.
Apple iPad – Purchase for download Photon Flash Player for iPad Flash App or iSwifter Flash App. Launch either of these Apps to access the course online site in order to logon to and view your course. Remember to adjust your audio.
~~~ Sorry, you cannot view this course on a Nook or Kindle. ~~~
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“I felt the course was moderately difficult but I learned lots!“
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TABLE OF CONTENTS
Part I: Structure of Herpes Simplex Virus
Part II: HSV Entry and Fusion:The Basics
Part III: The Viral Takeover: Cell Control, Replication and Egress
Part IV: HSV Latency
Part V: HSV Statistics and Disease
Part VI: Varicella Zoster Virus
Part VII: VZV Statistics and Disease
Part VIII: Specimen Collection and Testing
Part IX: Treatment of Alphaherpesvirus Infections