The Antiphospholipid Syndrome
Self-Study 260 – Intermediate Level
Contact Hours (Points): 2
Written by Michael J. Sanfelippo, MS, MT(ASCP)
At the end of the course you should be able to:
- Describe the occurrence and pathophysiology of the APS.
- List the current classification criteria for the APS.
- List the laboratory tests for identification of the APS and discuss their interpretations.
- Describe the specimen preparation necessary for the coagulation test for the APS.
- Define the Catastrophic Antiphospholipid Syndrome.
- Describe the effect of the lupus anticoagulant on tests used to monitor anticoagulant therapy.
- Discuss the use of alternative methods of monitoring anticoagulant therapy that are not subject to interference from the lupus anticoagulant.
Online 260: Course Taken Online: $27.00 BUY NOW
IMPORTANT: This online course is accessible using the following:
Desktop or Laptop Computer – Download the latest Adobe Reader program.
Kindle Fire – No additional App download is necessary.
Apple iPad (all versions) / Nook / Kindle – Recommend purchase of a PDF Reader App, such as GoodReader, Cloudreaders, or Stanza by Amazon. Once downloaded, launch this App to access the course online site in order to logon to and view your course.
TABLE OF CONTENTS
SECTION I: INTRODUCTION
Historical Perspective; Occurrence of the Antiphospholipid Syndrome; Pathophysiologyof the Antiphospholipid Syndrome; Diagnostic Criteria for the Antiphospholipid Syndrome
SECTION II: LABORATORY IDENTIFICATION OF THE ANTIPHOSPHOLIPID SYNDROME
Identification of the Lupus Anticoagulant; Laboratory Tests for the Lupus Anticoagulant; Activated Partial Thromboplastin Time (APTT); Hexagonal Phase Assay (PTT-Lupus Anticoagulant, PTT-LA); Dilute Russell Viper Venom Time; Prothrombin Time; Identification of Antibodies to Cardiolipin, Beta-2 glycoprotein 1 and phosphatidylserine /
SECTION III: CLINICAL PRESENTATION OF THE ANTIPHOSPHOLIPID SYNDROME
Hemorrhagic Complications of the Antiphospholipid Syndrome; Anticoagulant Therapy in Patients with Antiphospholipid Syndrome; Catastrophic Antiphospholipid Syndrome (CAP); Occurrence of CAP; Clinical Presentation of CAP; Laboratory Identification of CAP
SECTION IV: Case Study
Discussion of Laboratory Test Results; Treatment and Patient Outcome