Non-Alpha and Non-Beta Thalassemic Syndromes
Self-Study 274 – Intermediate Level
Contact Hours (Points): 3
Written by Tim Randolph, PhD, MT(ASCP) and Brooke L. Solberg, PhD, MLS(ASCP)CM
Originally written as sections of course #79 in 2000. Revised as Course #274 in 2015.
Online – 274: Course Taken Online: $40.00 BUY NOW
IMPORTANT: This online course is accessible using the following:
Desktop or Laptop Computer – Download the latest Adobe Reader program.
Kindle Fire – No additional App download is necessary.
Apple iPad (all versions) / Nook / Kindle – Recommend purchase of a PDF Reader App, such as GoodReader, Cloudreaders, or Stanza by Amazon. Once downloaded, launch this App to access the course online site in order to logon to and view your course.
TABLE OF CONTENTS
SECTION I: INTRODUCTION TO THALASSEMIA
Review of Hemoglobin Structure and Ontogeny; Thalassemias; Thalassemias vs Hemoglobinopathies
SECTION II: LABORATORY IMPLICATIONS IN THALASSEMIA
General Laboratory Findings in Thalassemia; Hematology Parameters; Microcytic/Hypochromic Red Blood Cells; Other Peripheral Blood Changes;
Hemoglobin Electrophoresis; Bone Marrow; Other Testing SECTION III: BETA THALASSEMIA
Etiology; Genetics; Beta Thalassemia Major; Expected genotypes; Individuals affected; Pathogenesis; Clinical Manifestations; Laboratory Results; Differential Diagnosis; Treatment; Prognosis; Beta Thalassemia Intermedia; Expected genotypes; Affected Individuals; Pathogenesis; Clinical Manifestations; Laboratory Results; Differential Diagnosis; Treatment and Prognosis; Prognosis; Beta Thalassemia Minor; Expected Genotypes; Affected Individuals; Pathogenesis; Clinical Manifestations; Laboratory Results; Differential Diagnosis; Treatment and Prognosis; Beta Thalassemia Minima
SECTION III: NON-ALPHA AND NON-BETA THALASSEMIC SYNDROMES
Hereditary Persistence of Fetal Hemoglobin
Thalassemias Associated with Structural Variants